'Audio stim' is very simply the use of audio files to control your electro-stimulator. By using audio, you allow for a broader range of rhythms and sensations than can be achieved with simple repeating pattern modes. The benefit of this is that you can set an intensity level that you enjoy, then lay back and enjoy a changing rhythm- hands free!
Plus, more advanced players can even make their own audio files that control the stimulation response exactly as desired. By stringing these files together you can create whole 'stories' that will manipulate your stimulation for your chosen length of time. There's a massive audio-stim community online, with many people sharing their audio files for free, so we also highly recommend checking out Joanne's Kinky Forum (which has an active e-stim community) and the e-stim tag on Reddit.
Our Flux and AXIS stimulators support stereostim play using a line-in input. This means that when you have a stereo track (that will have Left and Right channels), Flux and AXIS filter these so that the Left audio controls the left output and the Right controls the right output. Controlling the stimulation in this way means that the sensations can be much more dynamic and interesting.
We've created a few extended stereo-stim files that demonstrate just some of the possibilities available with audio play. Don't forget that audio-stim tracks aren't designed to be listened to like music, so it's perfectly normal if they sound strange!
If you're interested in making your own sessions, you can download a selection of library files we've created to help you make your own extended files. By using the free open source audio editing software, Audacity (download here: ) you can paste any of these files together to control your stimulation.
These downloadable files are divided into Synchronised (simultaneously fires channel 1 and 2) and Asynchronous (channel 1 and 2 have different patterns) folders for ease of use, but you can also mix and match these files in Audacity to create new and unusual sensations. Please click the links to automatically download a zip folder of library files which you can use to build your own tracks.
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Jean-Baptiste Mignardot/EPFLThree patients with partial or complete lower-limb paralysis can now walk with support thanks to electrical epidural stimulation, or EES, applied to the surface of their spinal cords.
Co-author Grégoire Courtine of the Swiss Federal Institute of Technology in Lausanne emphasized the importance of timing, both in the electrical stimulation process and in its future uses on patients:
The NHLBI stimulates basic discoveries about the causes of disease, enables the translation of basic discoveries into clinical practice, fosters training and mentoring of emerging scientists and physicians, and communicates research advances to the public. It creates and supports a robust, collaborative research infrastructure in partnership with private and public organizations, including academic institutions, industry, and other government agencies. The Institute collaborates with patients, families, health care professionals, scientists, professional societies, patient advocacy groups, community organizations, and the media to promote the application of research results and leverage resources to address public health needs. The NHLBI also collaborates with international organizations to help reduce the burden of heart, lung, and blood diseases worldwide.
An early-phase study at the NIH Clinical Center showed that eltrombopag, a drug that was designed to stimulate production of platelets from the bone marrow and thereby improve blood clotting, can raise blood cell levels in some people with severe aplastic anemia who have failed to benefit from standard therapies. Eltrombopag was approved by the FDA in August 2016 for patients with severe aplastic anemia who have not responded well to immunosuppressive therapy.
The Molecular Cellular and Systems Blood Science Branch provides oversight, support and stimulation of fundamental basic research and early stage laboratory translation of the biology of blood, blood forming elements, and the interface between each of the latter with other cellular and organ systems. Branch responsibilities include: 1) oversight, support and stimulation of discovery science focused on the explication of the physiology and pathophysiology of blood, bone marrow, and blood vessels; 2) oversight, support and stimulation of systems biological approaches to understanding the critical role of blood, bone marrow, and vascular endothelium in animal and human organs and organisms; 3) oversight, support, and stimulation of the application of fundamental genetics, proteomic and metabolomics tools to understanding hematologic physiology and pathophysiology; 4) administration of and/or liaison to NHLBI/NIH resources related to basic research in non-neoplastic hematology; and 5) fostering scientific communication across the Division, NHLBI, NIH and partner federal agencies.
The Translational Blood Science and Resources Branch provides oversight, support, and stimulation of translational research throughout the spectrum of blood science, as well as the resources required to support heart, lung, blood, and sleep research. Branch responsibilities will include: 1) oversight, support, and stimulation of post-discovery science, pre-clinical research, and early phase clinical studies and trials; 2) oversight, support, and stimulation of SBIR/STTR initiatives in the blood sciences; 3) administration of and/or liaison to NHLBI resources related to translational research; 4) training of the blood science workforce; and, 5) scientific liaison for translation research across the Division, NHLBI, NIH and partner federal agencies.
The Blood Epidemiology and Clinical Therapeutics Branch is responsible for oversight, support, and stimulation of epidemiologic, clinical, and implementation research throughout the spectrum of blood science. Branch responsibilities include: 1) oversight, support, and stimulation of epidemiologic, health services, and observational clinical research; 2) oversight, support, and stimulation of therapeutic and interventional clinical trials; 3) acquisition and maintenance of expertise in clinical study and trial design and administration on behalf of the Division; 4) oversight, support , and stimulation of implementation science and research; 5) training of the blood science workforce; and, 6) scientific liaison for epidemiologic, clinical, and implementation research across the Division, NHLBI, NIH and partner federal agencies.
Plus, more advanced players can even make their own audio files that control the stimulation response exactly as desired. By stringing these files together you can create whole 'stories' that will manipulate your stimulation for your chosen length of time. There's a massive audio-stim community online, with many people sharing their audio files for free, so we also highly recommend checking out www.smartstim.com
Older stimulators on the market (including our SensaVox unit) have two channels but only process audio in Mono, which means both outputs will only respond to the Left channel of the audio.
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